We back visionary founders who are building technologies of the future.

2048 Ventures is a thesis-driven early stage venture capital firm focused on Vertical AI, Deep Tech, Health and Bio. We invested in over 200 startups, and have the conviction to lead your pre-seed or seed round.

Pitch us

We get you and your vision before others

Our founders

We get to conviction quickly, and lead your round with $500K - $2M check. Our process is clear and transparent, we go from the first meeting to commitment to lead in 10-15 business days. We will never ghost you, and will never waste your time.  After we invest, we use our massive network and strong reputation to help you pull together rest of the round.

If you are a mission-driven team, with a strong founder market-fit and a vision for what the future should look like - we would love to meet you. Our goal is to partner with you day 0, earn your trust, and become the least annoying and most helpful investor on your cap table. We are proud to have a consistent NPS score of 100 from our founders.

We are not your typical early stage firm


We are thesis-driven investors, and invest in the next generation of platforms with strong data moats — Systems of Record, infrastructure and API companies in Vertical AI, Deep Tech, Health, and Bio.

We believe in long-term value and wealth creation through building companies that solve fundamental, vertical-specific problems.

We are based in NYC and Boston, but are happy to lead your pre-seed or seed anywhere across North America.

Who we are

We are a team of experienced founders, operators, engineers, and scientists who are passionate about working with founders at the earliest stage.

Alex Iskold

Founder and Partner

Zann Ali

Partner

Julie Wolf

Partner

Pitch us your startup.

You do not need a warm introduction to get in touch. You can pitch us directly as soon as you are ready using Pitch us button on top .

We are committed to reviewing 100% of the pitches we receive.

"Alex is one of the hardest working investors you can have on your cap table. He's not only invested in the business, he is invested in the founders."

Liz Giorgi
soona
Co-Founder + CEO

"Quick to compute, high conviction, and extremely helpful - especially for first-time founders. Puts in the time to help companies. Cannot recommend 2048 enough."

Dr. Milad Dagher
Nomic Bio
Co-Founder + CEO

"Laser sharp, thoroughly tactical, consistently clear, overly generous, and deeply empathetic...it will take you no time at all to realize that."

Danielle Cohen-Shohet
Gloss Genius
Co-Founder + CEO

"You are a model for early stage VCs and I love working with you!"

Sean Ammirati
Growth Signals
CEO

"Their investment process was super founder friendly. After investment, they’ve been equally impressive."

Dr. Karthik Raman
Persist AI
CEO

"I can’t recommend 2048 Ventures enough. They move fast, they move with conviction, and they understand the space better than anyone."

Caitlyn Leksana
Fazeshift
CEO

"Alex is a godsend to every company that he invests in. Not only is he vastly experienced and knowledgeable, but his integrity, loyalty and work-ethic are unparalleled."

Rahul Sidhu
Aerodome

"I consider Zann an extension of my founding team. He spends real time with me providing strategic advice and championing our business every step of the way."

Josh Stein
Impilo
CEO

"The investors at 2048 are incredible champions of scientific founders. Julie is the kind of investor that will roll up her sleeves and brainstorm with you at any time."

Dr. Caitlyn Miller
TwoStep Therapeutics
CEO